Aging
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Effect of Glycocalyx-targeted Therapy on Vascular Function in Older Adults: A Randomized Controlled Trial.
Gimblet CJ, Ernst JW, Bell B, Bos KD, Stroud AK, Wendt LH, Donato AJ, Jalal DI, Pierce GL.J Appl Physiol (1985). 2024 May 9.
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Advanced age results in a diminished endothelial glycocalyx.
Machin DR, Bloom SI, Campbell RA, Phuong TTT, Gates PE, Lesniewski LA, Rondina MT, Donato AJ.Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H531-H539.
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Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction
Daniel R Machin, Daniel W Trott, Venkateswara R Gogulamudi, Md Torikul Islam, Samuel I Bloom, Hans Vink, Lisa A Lesniewski, Anthony J Donato, Geroscience. 2023 Aug;45(4):2351-2365. doi: 10.1007/s11357-023-00745-1.