Published Papers

Effects of a single aerobic exercise on perfuse...

Abstract The endothelium and the glycocalyx play a pivotal role in regulating microvascular function and perfusion in health and critical illness. It is unknown today, whether aerobic exercise immediately affects...

Effects of a single aerobic exercise on perfuse...

Abstract The endothelium and the glycocalyx play a pivotal role in regulating microvascular function and perfusion in health and critical illness. It is unknown today, whether aerobic exercise immediately affects...

Association of COVID-19 with impaired endotheli...

Abstract Aims SARS-CoV-2 infection may lead to endothelial and vascular dysfunction. We investigated alterations of arterial stiffness, endothelial coronary and myocardial function markers 4 months after COVID-19 infection. Methods and...

Association of COVID-19 with impaired endotheli...

Abstract Aims SARS-CoV-2 infection may lead to endothelial and vascular dysfunction. We investigated alterations of arterial stiffness, endothelial coronary and myocardial function markers 4 months after COVID-19 infection. Methods and...

Managing sepsis and septic shock in an endothel...

  Abstract Maintaining tissue perfusion in sepsis depends on vascular integrity provided by the endothelial glycocalyx, the critical layer covering the luminal surface of blood vessels. The glycocalyx is composed...

Managing sepsis and septic shock in an endothel...

  Abstract Maintaining tissue perfusion in sepsis depends on vascular integrity provided by the endothelial glycocalyx, the critical layer covering the luminal surface of blood vessels. The glycocalyx is composed...

Long-term efficacy of liposomal nanocarriers of...

Abstract The endothelial glycocalyx (EG) undergoes early degradation in sepsis. Our recent work introduced a novel therapeutic approach involving liposomal nanocarriers of preassembled glycocalyx (LNPG) to restore EG in lipopolysaccharide...

Long-term efficacy of liposomal nanocarriers of...

Abstract The endothelial glycocalyx (EG) undergoes early degradation in sepsis. Our recent work introduced a novel therapeutic approach involving liposomal nanocarriers of preassembled glycocalyx (LNPG) to restore EG in lipopolysaccharide...

Doxycycline protects against sepsis-induced end...

Abstract Endothelial glycocalyx (eGC) covers the inner surface of the vessels and plays a role in vascular homeostasis. Syndecan is considered the “backbone” of this structure. Several studies have shown...

Doxycycline protects against sepsis-induced end...

Abstract Endothelial glycocalyx (eGC) covers the inner surface of the vessels and plays a role in vascular homeostasis. Syndecan is considered the “backbone” of this structure. Several studies have shown...

Effect of Glycocalyx-targeted Therapy on Vascul...

Abstract Advancing age increases cardiovascular disease risk, in part, because of impaired glycocalyx thickness and endothelial dysfunction. Glycocalyx-targeted therapies, such as Endocalyx Pro™, could improve both glycocalyx thickness and endothelial...

Effect of Glycocalyx-targeted Therapy on Vascul...

Abstract Advancing age increases cardiovascular disease risk, in part, because of impaired glycocalyx thickness and endothelial dysfunction. Glycocalyx-targeted therapies, such as Endocalyx Pro™, could improve both glycocalyx thickness and endothelial...