Sepsis/Shock
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Microcirculation, endothelium and glycocalyx changes associated with the use of milrinone in children with septic shock.
Sarta-Mantilla M, Fernández-Sarmiento J, Acevedo L, Mulett H, Nieto A, Lucena N, Lancheros J, Duque C.Transl Pediatr. 2024 May 31;13(5):727-737.
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Long-term efficacy of liposomal nanocarriers of preassembled glycocalyx in restoring cerebral endothelial glycocalyx in sepsis.
Ishiko S, Huang A, Sun D.Microvasc Res. 2024 Apr 23;154:104684.
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Biomarkers of endothelial glycocalyx damage are associated with microvascular dysfunction in resuscitated septic shock patients.
Soubihe Neto N, de Almeida MCV, Couto HO, Miranda CH.Microvasc Res. 2024 Mar 23;154:104683.
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The association between prolonged capillary refill time and microcirculation changes in children with sepsis.
Fernández-Sarmiento J, Lamprea S, Barrera S, Acevedo L, Duque C, Trujillo M, Aguirre V, Jimenez C.BMC Pediatr. 2024 Jan 20;24(1):68.
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Effect of high-dose intravenous ascorbic acid on micro-circulation and endothelial glycocalyx during sepsis and septic shock: a double-blind, randomized, placebo-controlled study.
Belousoviene E, Pranskuniene Z, Vaitkaitiene E, Pilvinis V, Pranskunas A.BMC Anesthesiol. 2023 Sep 12;23(1):309.
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The association between hypoalbuminemia and microcirculation, endothelium, and glycocalyx disorders in children with sepsis.
Fernández-Sarmiento J, Hernández-Sarmiento R, Salazar MP, Barrera S, Castilla V, Duque C. Microcirculation. 2023 Nov;30(8):e12829.
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Liposomal nanocarriers of preassembled glycocalyx expeditiously restore endothelial glycocalyx in endotoxemia.
Ishiko S, Ben Rahoma G, Kandhi S, Huang A, Sun D.Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H645-H655.
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Endothelial and Glycocalyx Biomarkers in Children With Sepsis After One Bolus of Unbalanced or Balanced Crystalloids.
Fernández-Sarmiento J, Salazar-Peláez LM, Acevedo L, Niño-Serna LF, Flórez S, Alarcón-Forero L, Mulett H, Gómez L, Villar JC.Pediatr Crit Care Med. 2023 Mar 1;24(3):213-221.
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Links between Endothelial Glycocalyx Changes and Microcirculatory Parameters in Septic Patients.
Belousoviene E, Kiudulaite I, Pilvinis V, Pranskunas A.Life (Basel). 2021 Aug 5;11(8):790.
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Identification of novel sublingual parameters to analyze and diagnose microvascular dysfunction in sepsis: the NOSTRADAMUS study.
Rovas A, Sackarnd J, Rossaint J, Kampmeier S, Pavenstädt H, Vink H, Kümpers P.Crit Care. 2021 Mar 19;25(1):112.
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Decreased endothelial glycocalyx thickness is an early predictor of mortality in sepsis.
Beurskens DM, Bol ME, Delhaas T, van de Poll MC, Reutelingsperger CP, Nicolaes GA, Sels JE.Anaesth Intensive Care. 2020 May;48(3):221-228.
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Variability of Microcirculatory Measurements in Critically Ill Patients.
Bol ME, Beurskens DMH, Delnoij TSR, Roekaerts PMHJ, Reutelingsperger CPM, Delhaas T, van de Poll MCG, Sels JEM, Nicolaes GAF.Shock. 2020 Jul;54(1):9-14.
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Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.
Drost CC, Rovas A, Kusche-Vihrog K, Van Slyke P, Kim H, Hoang VC, Maynes JT, Wennmann DO, Pavenstädt H, Linke W, Lukasz A, Hesse B, Kümpers P.Thromb Haemost. 2019 Nov;119(11):1827-1838.
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Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis.
Rovas A, Seidel LM, Vink H, Pohlkötter T, Pavenstädt H, Ertmer C, Hessler M, Kümpers P.Crit Care. 2019 Jul 24;23(1):260.
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Plasma free hemoglobin and microcirculatory response to fresh or old blood transfusions in sepsis.
Damiani E, Adrario E, Luchetti MM, Scorcella C, Carsetti A, Mininno N, Pierantozzi S, Principi T, Strovegli D, Bencivenga R, Gabrielli A, Romano R, Pelaia P, Ince C, Donati A.PLoS One. 2015 May 1;10(5):e0122655.
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Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study.
Donati A, Damiani E, Luchetti M, Domizi R, Scorcella C, Carsetti A, Gabbanelli V, Carletti P, Bencivenga R, Vink H, Adrario E, Piagnerelli M, Gabrielli A, Pelaia P, Ince C.Crit Care. 2014 Feb 17;18(1):R33.
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The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome.
Donati A, Damiani E, Botticelli L, Adrario E, Lombrano MR, Domizi R, Marini B, Van Teeffelen JW, Carletti P, Girardis M, Pelaia P, Ince C.BMC Anesthesiol. 2013 Sep 26;13(1):25.
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Alteration of the sublingual microvascular glycocalyx in critically ill patients.
Donati A, Damiani E, Domizi R, Romano R, Adrario E, Pelaia P, Ince C, Singer M.Microvasc Res. 2013 Nov;90:86-9.
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Doxycycline protects against sepsis-induced endothelial glycocalyx shedding.
de Oliveira JGCG, Miranda CH.Sci Rep. 2024 May 7;14(1):10477.
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Protection and rebuilding of the endothelial glycocalyx in sepsis - Science or fiction?
Drost CC, Rovas A, Kümpers P.Matrix Biol Plus. 2021 Nov 3;12:100091.
26 peer-reviewed papers on sepsis, shock and critical care
Studies tagged “Sepsis & critical care” in our indexed library, each with a plain-English summary, the study type and a link to the journal. Or ask the library a question in your own words.