Exercise & performance: 2 papers
Peer-reviewed work on the endothelial glycocalyx, microvascular health and the ingredients in our formulas, newest first. Abstracts are indexed here and every paper links to the journal.
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Published paper
Effects of a single aerobic exercise on perfused boundary region and microvascular perfusion: a field study
This observational field study measured sublingual microvascular glycocalyx dimensions (perfused boundary region, PBR) and red blood cell filling percentage using sidestream dark-field imaging with GlycoCheck software in 14 healthy adults immediately before and after a 10 km trail run. A single bout of aerobic exercise produced no significant change in PBR, RBC filling percentage, or capillary density. However, individual changes in PBR were inversely associated with changes in RBC filling percentage, suggesting that a thicker endothelial surface layer accompanies better microvascular perfusion.
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Published paper
Effects of high-intensity interval training on microvascular glycocalyx and associated microRNAs
Fifty healthy young adults completed a 4-week high-intensity interval training (HIIT) program consisting of 4 x 30-s all-out runs, with sublingual microvascular imaging (sidestream dark-field, perfused boundary region) before and after. Exercise capacity correlated with glycocalyx measures, and several circulating microRNAs were upregulated by HIIT, with baseline miR-143 predicting later glycocalyx changes. The authors conclude HIIT alters the endothelial glycocalyx of the microvasculature and that miRNAs may serve as markers of early vascular adaptation.
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